Substance |
Info | Dose |
Warn | Link |
PubMed |
Latest article |
Curcumin | 📋 | ✍ | ⛔ | | 34567112 | Plant Natural Compounds in the Treatment of Adrenocortical Tumors |
DHEA | 📋 | ✍ | ⛔ | | 34342920 | Effects of dehydroepiandrosterone (DHEA) supplementation on cortisol, leptin, adiponectin, and liver enzyme levels: a systematic review and meta-analysis of randomized clinical trials |
Melatonin | 📋 | ✍ | ⛔ | | 36642730 | Melatonin alleviates PTSD-like behaviors and restores serum GABA and cortisol levels in mice |
Vitamin C | 📋 | ✍ | ⛔ | | 38010274 | Vitamin C supplementation alleviates hypercortisolemia caused by chronic stress |
Vitamin D3 | 📋 | ✍ | ⛔ | | 36313775 | Vitamin D and adrenal gland: Myth or reality? A systematic review |
Ashwagandha | 📋 | ✍ | ⛔ | | 38140274 | Effects of Withania somnifera on Cortisol Levels in Stressed Human Subjects: A Systematic Review |
Lavender Essential Oil | 📋 | ✍ | ⛔ | | 35708557 | The Effect of Aromatherapy on Blood Pressure and Stress Responses by Inhalation and Foot Massage in Patients With Essential Hypertension: Randomized Clinical Trial |
Caffeine | 📋 | ✍ | ⛔ | | 20737165 | Caffeinated chewing gum increases repeated sprint performance and augments increases in testosterone in competitive cyclists |
Genistein | 📋 | ✍ | ⛔ | | 11354798 | [Inhibitory Effect of Genistein on the Proliferation of the Anterior Pituitary Cells of Rats] |
Magnolia | 📋 | ✍ | ⛔ | | 16454147 | Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial |
Metformin | 📋 | ✍ | ⛔ | | 38147953 | Metformin inhibits cell proliferation and ACTH secretion in AtT20 cells via regulating the MAPK pathway |
Phosphatidylserine | 📋 | ✍ | ⛔ | | 18662395 | The effects of phosphatidylserine on endocrine response to moderate intensity exercise |
Tangeretin | 📋 | | | | 35665223 | Effects of 4-Week Tangeretin Supplementation on Cortisol Stress Response Induced by High-Intensity Resistance Exercise: A Randomized Controlled Trial |
Vitamin B5 | 📋 | ✍ | ⛔ | | 18520055 | Effects of pantothenic acid supplementation on adrenal steroid secretion from male rats |
Asiaticoside | 📋 | | | | 38599249 | Biomarker triterpenoids of Centella asiatica as potential antidepressant agents: Combining in vivo and in silico studies |
Asparagus | 📋 | | ⛔ | | 37755852 | Beneficial Effects of Asparagus officinalis Extract Supplementation on Muscle Mass and Strength following Resistance Training and Detraining in Healthy Males |
Aspirin | 📋 | | ⛔ | | 36059148 | Aspirin mediates its antitumoral effect through inhibiting PTTG1 in pituitary adenoma |
Avocado Oil | 📋 | | ⛔ | | 33480081 | Avocado oil (Persea americana) protects SH-SY5Y cells against cytotoxicity triggered by cortisol by the modulation of BDNF, oxidative stress, and apoptosis molecules |
Baicalin | 📋 | ✍ | ⛔ | | 17639560 | Schizandra Chinensis and Scutellaria Baicalensis Counter Stress Behaviors in Mice |
Bay Leaf | 📋 | | ⛔ | | 36881915 | Evaluation of daily Laurus nobilis tea consumption on anxiety and stress biomarkers in healthy volunteers |
BCAA | 📋 | ✍ | ⛔ | | 36177954 | Peripheral fatigue and hormone responses to branched-chain amino acids ingestion and exercise in recovery: a systematic review and meta-analysis |
Bergamot Essential Oil | 📋 | ✍ | ⛔ | | 25824404 | Effects of bergamot ( Citrus bergamia (Risso) Wright & Arn.) essential oil aromatherapy on mood states, parasympathetic nervous system activity, and salivary cortisol levels in 41 healthy females |
Beta-Carotene | 📋 | ✍ | ⛔ | | 23667519 | Lycopene and beta-carotene induce growth inhibition and proapoptotic effects on ACTH-secreting pituitary adenoma cells |
Beta-Sitosterol | 📋 | ✍ | ⛔ | | 15877297 | Cortitrol supplementation reduces serum cortisol responses to physical stress |
Cocoa | 📋 | ✍ | ⛔ | | 19810704 | Metabolic effects of dark chocolate consumption on energy, gut microbiota, and stress-related metabolism in free-living subjects |
Coffee | 📋 | ✍ | ⛔ | | 16814782 | Coffee inhibits the reactivation of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: a glucocorticoid connection in the anti-diabetic action of coffee? |
D-Ribose | 📋 | ✍ | ⛔ | | 35684021 | A Combination of Nicotinamide and D-Ribose (RiaGev) Is Safe and Effective to Increase NAD + Metabolome in Healthy Middle-Aged Adults: A Randomized, Triple-Blind, Placebo-Controlled, Cross-Over Pilot Clinical Trial |
Daidzein | 📋 | ✍ | ⛔ | | 10404819 | Phytoestrogens Alter Adrenocortical Function: Genistein and Daidzein Suppress Glucocorticoid and Stimulate Androgen Production by Cultured Adrenal Cortical Cells |
Eleuthero | 📋 | ✍ | ⛔ | | 15507373 | Effects of various Eleutherococcus senticosus cortex on swimming time, natural killer activity and corticosterone level in forced swimming stressed mice |
Fish Oil | 📋 | ✍ | ⛔ | | 20932294 | Effects of supplemental fish oil on resting metabolic rate, body composition, and salivary cortisol in healthy adults |
HMB | 📋 | ✍ | ⛔ | | 36171789 | Testosterone and cortisol responses to ß-hydroxy ß-methylbutryate consumption and exercise: A meta-analysis |
Holy Basil | 📋 | ✍ | ⛔ | | 37141281 | Ocimum tenuiflorum extract (HOLIXERTM): Possible effects on hypothalamic-pituitary-adrenal (HPA) axis in modulating stress |
L-Arginine | 📋 | ✍ | ⛔ | | 17510493 | Oral Treatment With L-lysine and L-arginine Reduces Anxiety and Basal Cortisol Levels in Healthy Humans |
L-Lysine | 📋 | ✍ | ⛔ | | 17510493 | Oral Treatment With L-lysine and L-arginine Reduces Anxiety and Basal Cortisol Levels in Healthy Humans |
L-Theanine | 📋 | ✍ | ⛔ | | 15877297 | Cortitrol supplementation reduces serum cortisol responses to physical stress |
L-Tryptophan | 📋 | ✍ | ⛔ | | 15996691 | Surplus dietary tryptophan reduces plasma cortisol and noradrenaline concentrations and enhances recovery after social stress in pigs |
Lemon Verbena | 📋 | | ⛔ | | 35011093 | Anxiolytic Effect and Improved Sleep Quality in Individuals Taking Lippia citriodora Extract |
Licorice Root | 📋 | ✍ | ⛔ | | 17594790 | Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease |
Lycopene | 📋 | ✍ | ⛔ | | 23667519 | Lycopene and beta-carotene induce growth inhibition and proapoptotic effects on ACTH-secreting pituitary adenoma cells |
Madecassoside | 📋 | | | | 38599249 | Biomarker triterpenoids of Centella asiatica as potential antidepressant agents: Combining in vivo and in silico studies |
Milk Thistle | 📋 | ✍ | ⛔ | | 18817226 | Effect of silymarin on metabolic factors of food-restricted over conditioned Wistar rats |
MSM | 📋 | ✍ | ⛔ | | 31853292 | Methylsulfonylmethane inhibits cortisol-induced stress through p53-mediated SDHA/HPRT1 expression in racehorse skeletal muscle cells: A primary step against exercise stress |
Neem | 📋 | ✍ | | | 35198760 | Anxiolytic and antidepressant-like activities of aqueous extract of Azadirachta indica A. Juss. flower in the stressed rats |
Nicotinamide | 📋 | ✍ | ⛔ | | 35684021 | A Combination of Nicotinamide and D-Ribose (RiaGev) Is Safe and Effective to Increase NAD + Metabolome in Healthy Middle-Aged Adults: A Randomized, Triple-Blind, Placebo-Controlled, Cross-Over Pilot Clinical Trial |
Omega-3 Fatty Acids | 📋 | ✍ | ⛔ | | 33875799 | Omega-3 supplementation and stress reactivity of cellular aging biomarkers: an ancillary substudy of a randomized, controlled trial in midlife adults |
Onion | 📋 | ✍ | ⛔ | | 35745673 | Quercetin-Rich Extracts from Onions ( Allium cepa) Play Potent Cytotoxicity on Adrenocortical Carcinoma Cell Lines, and Quercetin Induces Important Anticancer Properties |
Phellodendron | 📋 | ✍ | ⛔ | | 16454147 | Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial |
Phosphatidylcholine | 📋 | ✍ | ⛔ | | 15877297 | Cortitrol supplementation reduces serum cortisol responses to physical stress |
Phytoestrogens | 📋 | | ⛔ | | 17867463 | Phytoestrogens alter cortisol and androstenedione secretion by porcine adrenocortical cells |
Pomegranate | 📋 | | ⛔ | | 36358496 | Antioxidant Properties and Beneficial Cardiovascular Effects of a Natural Extract of Pomegranate in Healthy Volunteers: A Randomized Preliminary Single-Blind Controlled Study |
Progesterone | 📋 | ✍ | ⛔ | | 37047801 | Preclinical Evidence of Progesterone as a New Pharmacological Strategy in Human Adrenocortical Carcinoma Cell Lines |
Quercetin | 📋 | ✍ | ⛔ | | 35745673 | Quercetin-Rich Extracts from Onions ( Allium cepa) Play Potent Cytotoxicity on Adrenocortical Carcinoma Cell Lines, and Quercetin Induces Important Anticancer Properties |
Rosemary Essential Oil | 📋 | ✍ | ⛔ | | 17291597 | Smelling lavender and rosemary increases free radical scavenging activity and decreases cortisol level in saliva |
Schisandra | 📋 | ✍ | ⛔ | | 17639560 | Schizandra Chinensis and Scutellaria Baicalensis Counter Stress Behaviors in Mice |
Sea Buckthorn | 📋 | ✍ | ⛔ | | 26684638 | Sea buckthorn (Hippophae rhamnoides L.) oil protects against chronic stress-induced inhibitory function of natural killer cells in rats |
St. Johns Wort | 📋 | ✍ | ⛔ | | 14659982 | Sub-chronic treatment with an extract of Hypericum perforatum (St John's wort) significantly reduces cortisol and corticosterone in the rat brain |
Tomato | 📋 | | ⛔ | | 38583186 | Does tomato juice consumption have a positive effect on the physical and psychological states of individuals in the Coronavirus era? |
TUDCA | 📋 | ✍ | ⛔ | | 31814847 | Tauroursodeoxycholic acid mediates endoplasmic reticulum stress and autophagy in adrenocortical carcinoma cells |
Vitamin E | 📋 | ✍ | ⛔ | | 17414802 | Antioxidant supplementation and immunoendocrine responses to prolonged exercise |